Robotic Therapy and Brain Stimulation in the Early Phase After Stroke

Recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

Ischemic or hemorrhagic stroke onset from 3 days to 9 weeks before, confirmed by computed tomography or magnetic resonance imaging.
Motor impairment of an upper limb, defined as a score between 1 - 3 in the Medical Research Council Scale, for at lest one the following movements: elbow extension, shoulder flexion, or shoulder extension.
Ability to provide written informed consent.
Ability to comply with the schedule of interventions and evaluations in the protocol.

Exclusion Criteria

Severe spasticity at the paretic elbow, wrist or fingers, defined as a score of > 3 in the Modified Ashworth Spasticity Scale.
No active shoulder and elbow movements
Uncontrolled medical problems such as end-stage cancer or renal disease
Pregnancy
Potential contraindications to transcranial direct current stimulation: history of seizures, lesions on the scalp, intracranial metal implants, prior intracranial surgery, use of drugs that interfere on cortical excitability (such as antiepileptic drugs, benzodiazepines)
Other neurological disorders such as Parkinson's disease
Psychiatric illness
Aphasia or severe cognitive deficits that compromise comprehension of the experimental protocol or ability to provide consent.
Hemineglect
Cerebellar lesions or on cerebellar pathways
Contact precautions