Robot Assisted Upper Limb Neuro-Rehabilitation

Completed

Phase 2 Results N/A

Trial Description

Our long term objectives are to understand the mechanisms of motor impairment following neurologic injury and to develop interventions to improve motor recovery. A series of complementary, overlapping clinical trials and development activities will validate and optimize the use of robot-assisted upper limb therapy for neuro rehabilitation.
We have developed a robotic system that assists or resists elbow and shoulder movements in three dimensional space. In addition to unilateral exercise modes, a novel bimanual mode enables hemiparetic subjects to practice mirror image upper limb exercises.

Detailed Description

Randomized controlled clinical trial of the Mirror Image Movement Enabler (MIME) robotic device for shoulder and elbow neurorehabilitation in subacute stroke patients. MIME incorporates a PUMA 560 robot that applies forces to the paretic limb during unilateral and bilateral movements in three dimensions. Robot-assisted treatment (bilateral, unilateral, and combined bilateral and unilateral) was compared with conventional therapy.

Conditions

Interventions

  • Traditional Therapy Other
    Other Names: 'Community based' Traditional therapy program
    Intervention Desc: 1 hour/day of upper limb therapy that includes exposure to, but no manipulation by the robot
    ARM 1: Kind: Experimental
    Label: 2
    Description: 1 hour/day of upper limb therapy that includes exposure to, but no manipulation by the robot
  • Robot-assisted therapy Other
    Intervention Desc: 1 hour/day of mechanically-assisted upper limb therapy
    ARM 1: Kind: Experimental
    Label: 1
    Description: 1 hour/day of mechanically-assisted upper limb therapy

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Fugl-Meyer score end of training, 6-month follow-up No

Sponsors