Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease "COMPASS"

Active, not recruiting

Phase 3 Results N/A

Eligibility Criteria

Inclusion Criteria

-- Coronary or peripheral artery disease
Patients with coronary artery disease must also meet at least one of the following:
- Age ≥65, or
- Age <65 and documented atherosclerosis or revascularization involving at least 2 vascular beds, or at least 2 additional risk factors

Exclusion Criteria

- Need for dual antiplatelet therapy, other non-aspirin antiplatelet therapy or oral anticoagulant therapy
- Stroke within 1 month or any history of hemorrhagic or lacunar stroke
- Severe heart failure with known ejection fraction <30% or New York Heart Association (NYHA) class III or IV symptoms
- Estimated glomerular filtration rate (eGFR)<15 mL/min