Rhythm Control of AF in Patients With Acute Stroke

Not yet recruiting

Phase N/A Results N/A

Trial Description

Prospective randomized (rhythm control or rate control) Objective of study
1. To analyze long term outcome of patients with acute stroke with atrial fibrillation according to the rhythm control
2. To analyze recurrence rate of atrial fibrillation or recurrence stroke in patients with acute stroke according to the rhythm control (by antiarrhythmic drug, cardioversion, catheter ablation)

Conditions

Interventions

  • Rate control Procedure
    Intervention Desc: No AAD, just anticoagulation HR control between 60~110bpm (with beta blocker, calcium channel blocker, digoxin) Without the treatment about antiarrhythmia and rhythm control, deification of rate control, the subject will be drop out for study.
    ARM 1: Kind: Experimental
    Label: Rate control group
    Description: No AAD, just anticoagulation HR control between 60~110bpm (with beta blocker, calcium channel blocker, digoxin) Without the treatment about antiarrhythmia and rhythm control, deification of rate control, the subject will be drop out for study.
  • Rhythm Control Procedure
    Intervention Desc: Start AAD right after evaluating for LA size, EF, LA thrombus, and presence of CAD during anticoagulation Cardioversion after 1 month Rhythm FU schedule (2012 ACC/AHA/ESC guidelines) If AF recur, RFCA
    ARM 1: Kind: Experimental
    Label: Rhythm control group
    Description: Start AAD right after evaluating for LA size, EF, LA thrombus, and presence of CAD during anticoagulation Cardioversion after 1 month Rhythm FU schedule (2012 ACC/AHA/ESC guidelines) If AF recur, RFCA

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary acute stroke with AF 1 year No
Primary recurrence of silence stroke 1 year No
Primary recurrence of AF after rhythm control 1 year No

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