Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited. The development of new treatment strategies is essential. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method to stimulate the focal area of the brain for restoring brain function. The aim of this study is to investigate the therapeutic effect of rTMS on the motor recovery in patients with hemiplegic stroke.
- Sham rTMS Device
ARM 1: Kind: Experimental Label: Sham rTMS Description: Participants will receive sham cTBS rTMS to contralesional hemisphere.
- Traditional Theta burst stimulation (TBS) Device
ARM 1: Kind: Experimental Label: Tradtional Theta burst stimulation (TBS) rTMS Description: Participants will receive continuous theta burst stimulation (cTBS) rTMS to contralesional hemisphere based on a previous study (Huang et al., 2005)
- Modified TBS rTMS Device
ARM 1: Kind: Experimental Label: Modified TBS rTMS Description: Participants will receive modified cTBS rTMS to contralesional hemisphere based on a previous study (Nyffeler et al., 2006)
- Allocation: Randomized
- Masking: Single Blind (Subject)
- Purpose: Treatment
- Endpoint: Safety/Efficacy Study
- Intervention: Parallel Assignment
|Type||Measure||Time Frame||Safety Issue|
|Primary||Keyboard tapping test||1 day||No|