Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke

Recruiting

Phase N/A Results N/A

Trial Description

Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited. The development of new treatment strategies is essential. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method to stimulate the focal area of the brain for restoring brain function. The aim of this study is to investigate the therapeutic effect of rTMS on the motor recovery in patients with hemiplegic stroke.

Conditions

Interventions

  • Sham rTMS Device
    ARM 1: Kind: Experimental
    Label: Sham rTMS
    Description: Participants will receive sham cTBS rTMS to contralesional hemisphere.
  • Traditional Theta burst stimulation (TBS) Device
    ARM 1: Kind: Experimental
    Label: Tradtional Theta burst stimulation (TBS) rTMS
    Description: Participants will receive continuous theta burst stimulation (cTBS) rTMS to contralesional hemisphere based on a previous study (Huang et al., 2005)
  • Modified TBS rTMS Device
    ARM 1: Kind: Experimental
    Label: Modified TBS rTMS
    Description: Participants will receive modified cTBS rTMS to contralesional hemisphere based on a previous study (Nyffeler et al., 2006)

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Subject)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Keyboard tapping test 1 day No

Sponsors