REperfusion With Cooling in CerebraL Acute IscheMia II "RECCLAIM-II"


Phase 2 Results N/A

Summary of Purpose

The purpose of this study is to determine whether reducing a patient's body temperature (mild hypothermia of 33 degrees Centigrade) will significantly reduce the risk of brain injury (notably reperfusion injury and hemorrhagic conversion) in patients who have suffered a significant interruption of blood flow to an area... Trial Stopped: It was decided that it was not feasible to continue this study.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 16 February 2016.

1 Feb 2016 25 Mar 2015 1 Nov 2017 1 Nov 2017 1 Feb 2016 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Prevention
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment


  • Rishi Gupta, MD

  • Christopher Horn, MD