Reduction of In-hospital Delays in Stroke Thrombolysis: SITS-WATCH "SITS-WATCH"

Recruiting

Phase N/A Results N/A

Trial Description

In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). SITS-WATCH aims to reduce median DNT in participating centres.

Detailed Description

In patients with acute ischemic stroke: the sooner the thrombolysis treatment is administered after symptom onset - the better the outcome. This delay can be dissected into onset-to-door time and door-to-needle time (DNT). Of the two, DNT can be directly influenced within the hospital by stream-lining of acute stroke care. The aim of our study is to reduce in-hospital delays (DNT) in self-selecting centers recruiting patients into the the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) , comprising currently more than 80 000 patients from 1338 centers. Current median of DNT in all SITS centers is 65 minutes (compared with 20 minutes in Helsinki Univer-sity Central Hospital). An itemized detailed questionnaire, including all factors known to influence DNT, has been sent to all SITS centers to identify the reasons for long in-hospital delays. Based on the replies, we have prepared a list of interventions that can be considered by individual SITS centers in order to reduce DNT with interventions that are in line with national legislation.

Conditions

Interventions

  • Reduction of DTN Other
    Intervention Desc: 15-item list of suggested interventions aiming to reduce DNT sent to SITS-WATCH centers.
    ARM 1: Kind: Experimental
    Label: Intervention group (SITS-WATCH centers)
    Description: 15-item list of suggested interventions aiming to reduce DNT sent to SITS-WATCH centers.

Trial Design

  • Allocation: Non-Randomized
  • Masking: Open Label
  • Purpose: Health Services Research
  • Intervention: Single Group Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Absolute DNT reduction of at least 20 minutes or at least 20% change in SITS-WATCH centers that completed the whole study period January 2013-December 2014 Yes
Secondary Significantly larger reduction of DNT in SITS-WATCH centers compared with non-SITS-WATCH centers in SITS. 2014-2015 Yes

Sponsors