Recovery of Impairments Early After Stroke "aRISE"

Not yet recruiting

Phase N/A Results N/A

Trial Description

Upper limb recovery after stroke is highly predictable early after stroke. Nijland et al. showed that based on two simple clinical bedside tests - 'Shoulder Abduction' and 'Finger Extension' (the so called 'SAFE model' [Stinear et al., 2012]) - measured within the first 72 hours after stroke, ~87% of the patients could be correctly classified as either regaining or not regaining some dexterity (recoverers or nonrecoverers, respectively) (Nijland et al., 2010). This kind of information regarding the patients' functional prognosis allows proper discharge planning, setting realistic rehabilitation goals, and adequate patient information. However, the length of hospital stay after stroke has been decreasing. Therefore, knowledge is needed regarding the ability to make an accurate first prediction within the first 24 hours after stroke onset while using simple clinical bedside assessments. This would facilitate an earlier triage and with that, an accelerated and smooth transition of patients within the stroke care continuum. In addition, a first prediction within 24 hours poststroke has the potential to decrease health care expenses, as length of hospital stay after an acute stroke is ~30% of the total costs (i.e., direct and indirect costs) associated with stroke (Roger et al., 2012; Fattore et al., 2012).
The primary objective of aRISE is to determine the ability of the behavioral biometric impairments 'Shoulder Abduction' and 'Finger Extension' measured <24 hours poststroke to predict outcome of upper limb capacity 3 months after stroke. The secondary aim is to investigate the the added value of other simple clinical bedside tests for predicting outcome of upper limb capacity 2 months poststroke.
aRISE is a prospective longitudinal observational cohort study of 40 first-ever ischemic stroke patients, who will be assessed <24 hours, 7 days and 3 months after stroke onset.

Conditions

Interventions

  • Assessment of behavioral biometric impairments Behavioral
    Intervention Desc: Assessment of behavioral biometric impairments
    ARM 1: Kind: Experimental
    Label: Single-group study
    Description: Assessment of behavioral biometric impairments

Trial Population

First-ever unilateral ischemic stroke patients, admitted to hospital

Outcomes

Type Measure Time Frame Safety Issue
Primary Action Research Arm Test 3 months poststroke
Primary Fugl-Meyer Assessment 3 months poststroke
Primary Motricity Index 3 months poststroke

Sponsors