Randomized trial of immediate anticoagulation of embolic stroke


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

Cardiogenic embolic brain infarction presenting within 48 hours of onset.

Exclusion Criteria

Pregnant females, bloody or xanthochromic CSF, persistent hypertension (BP > 180/115 mmHg), active peptic ulcer disease or occult blood in the stool, hemorrhagic infarction on initial CT, serum creatinine > 4.0 mg/dl, severe anemia (< 9 gm/dl) or thrombocytopenia, over 78 years of age or less than 18, mentally incompetent, history of heparin allergy or prior adverse reaction to heparin, therapeutic anticoagulation with coumadin at the time of stroke.