To determine the value of oral nimodipine 120 mg per day for acute stroke.
- Nimodipine (Nimotop®)Drug
Other Names: The treatment group Intervention Desc: Calcium channel blocker (L-type calcium channels)
Randomized, double-blind, placebo-controlled multicenter study of 1215 patients at 17 British centers.
Patients were randomized to receive 120 mg oral nimodipine (n=608) or placebo (n=607).
|Type||Measure||Time Frame||Safety Issue|
|Primary||Independence after 6 months, defined as a score of 60 or more on the Barthel index.|
|Secondary||Mortality, Nottingham ADL score, change in Orgogozo neurological score.|