The high levels of fatigue in stroke patients without neurological impairment suggest it has a central origin rather than being the result of increased physical effort required after stroke（Winward et al., 2009）. Fatigue is different from post-stroke depression and the more serious stroke patients are more prone to fatigue（Windward et al., 2009）.
Fatigue is one of the symptoms of qi deficiency,and Astragalus membranaceus is the most effective of all traditional Chinese medicine and can tonifying middle and tonify the original qi. Therefore, the aim of this study was to investigate the efficacy of Astragalus membranaceus on post-stroke fatigue.
- Placebo Drug
Intervention Desc: at a rate of 2.8g three times per day ARM 1: Kind: Experimental Label: Placebo
- Chinese Herb Astragalus membranaceus Drug
Intervention Desc: Astragalus membranaceus(AM)at a rate of 2.8g three times per day ARM 1: Kind: Experimental Label: Chinese Herb Astragalus membranaceus
- Allocation: Randomized
- Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
- Purpose: Treatment
- Endpoint: Safety/Efficacy Study
- Intervention: Parallel Assignment
|Type||Measure||Time Frame||Safety Issue|
|Primary||EORTC QLQ-C30||2 year(all patients)||Yes|
|Primary||BFI-T score||2 years(all patients)||Yes|
|Secondary||SF-36 score||2 years(all patients)||Yes|