To study the result of intravenous fluid in patients with acute ischemic stroke within 72 hours.
This study aims to find the effect of early IV fluid administration to patients with acute ischemic stroke on the neurological outcome and to determine the side effects of intravenous fluids. Due to its cost effectiveness and wide accessibility, the possible application or use of IV fluid infusion as first line treatment can aide in the treatment of more acute ischemic stroke patients worldwide. This novel information will aide physicians with more comprehensive understanding of the efficacy of utilizing IV fluid in future treatment plans for patients with acute ischemic stroke.
Trial Stopped: More progressive stroke in one arm
- 0.9% NaCl solution Drug
Other Names: Normal saline Intervention Desc: 0.9% NaCl solution intravenous infusion: 100 ml/hr for three days. ARM 1: Kind: Experimental Label: IV Fluid Description: 0.9% NaCl solution infusion: 100 ml/hr for three days.
- Allocation: Randomized
- Masking: Single Blind (Outcomes Assessor)
- Purpose: Treatment
- Endpoint: Efficacy Study
- Intervention: Parallel Assignment
|Type||Measure||Time Frame||Safety Issue|
|Primary||NIHSS ≤ 4||day 7 after treatment or on the day of discharge||No|
|Secondary||mRS ≤ 1||day 7 after treatment or on the day of discharge||No|
|Secondary||mRS ≤ 4||at day 90||No|
|Secondary||change of serum osmolarity||at day 3 after treatment||No|