PBA is a neurologic condition that is estimated to impact over a million patients and their families in the United States. PBA occurs secondary to an otherwise unrelated neurologic disease or injury, and manifests as involuntary, frequent, and disruptive outbursts of crying and/or laughing. Progress has been made in better understanding this debilitating condition, but much more needs to be done. That's why a new PBA patient registry, PRISM (Pseudobulbar Affect RegIstry Series), has been initiated.
The goal of PRISM is to establish the prevalence and quality of life (QOL) impact of PBA in patients with underlying neurologic conditions including
- Alzheimer's disease
- Amyotrophic lateral sclerosis
- Multiple sclerosis
- Parkinson's disease
- Traumatic brain injury
Because this is an observational registry, it doesn't require you to intervene with any specific treatment or procedure. Your participation allows the PRISM registry to collect and analyze data from your site and also compare it to national numbers captured in the PRISM registry about PBA across all of the major at-risk neurologic populations.
- Parkinson's Disease
- Traumatic Brain Injury
- Alzheimer's Disease
- Amyotrophic Lateral Sclerosis (ALS)
- Multiple Sclerosis (MS)
The population for this study will be 18 years and over
|Type||Measure||Time Frame||Safety Issue|
|Primary||Prevalence of PBA (using CNS-LS)||Upon Study Enrollment/Entry||No|