Eligibility Criteria

Inclusion Criteria

- Clinical diagnosis of ischemic stroke within 120 days
- Adult aged 20 years or older
- High risk of hemorrhagic stroke (history of intracranial hemorrhage or imaging evidence of previous intracranial hemorrhage)
- Informed consent

Exclusion Criteria

- Clinical diagnosis of myocardial infarction or coronary intervention within 4 weeks
- Bleeding tendency
- Pregnant or breast-feeding woman
- Hemorrhagic stroke within 6 months
- Patient who was taking antithrombotic medication other than aspirin and does not agree to change the previous medication
- Severe cardiovascular disease such as cardiomyopathy or congestive heart failure
- Life expectancy less than one year
- Contraindication to long term aspirin use
- Enrolled in other clinical trial within 30 days