Predictors of Early Chest Infection in Acute Ischemic Stroke "PRECAST"


Phase N/A Results N/A

Trial Description

Pneumonia is a frequent complication of acute stroke and is associated with increased mortality and long-term impairment in the affected subjects. In previous studies, a number of clinical (e.g., dysphagia, severe neurological impairment, mechanical ventilation), radiological (e.g., large infarctions in the territory of middle cerebral artery, insular infarction) and biochemical (e.g., increased serum levels of C-reactive protein, decreased levels of CD4+ T-lymphocytes) findings have been reported as risk factors of stroke-related chest infection. The present study (PRECAST) aims to identify a small set out of these previously described risk factors that can predict stroke-related pneumonia with high sensitivity and specificity.


Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Probability Sample

Trial Population

Acute ischemic stroke patients admitted to the neurological intensive care unit or stroke unit within 24 hours after stroke onset


Type Measure Time Frame Safety Issue
Primary diagnosis of chest infection within 7 days after stroke days 1-7 after stroke No