Post-Embolic Rhythm Detection With Implantable Versus External Monitoring "PERDIEM"

Active, not recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Diagnosis of the index event* made by a stroke specialist of an acute ischemic stroke or TIA occurring within the previous 90 days. The event must be either:
1. an arterial ischemic stroke confirmed by neuroimaging; or
2. transient ischemic attack with diffusion weighted positive lesion on MRI
- At least one 12-lead ECG has already been obtained as part of the routine clinical post-stroke/TIA work-up, and no ECGs have shown any episodes of atrial fibrillation or atrial flutter
- The patient is being actively investigated for the etiology of the stroke/TIA event and additional cardiac monitoring is desired to screen further for the possibility of occult paroxysmal atrial fibrillation/flutter
- Age 18 years or older
- Informed consent from the patient
- The patient is expected to survive at least 6 months.

Exclusion Criteria

- Any previously documented atrial fibrillation or atrial flutter, i.e. a past history of atrial fibrillation/flutter or atrial fibrillation/flutter detected on ECG, Holter, or telemetry following the index stroke/TIA event (a remote history of transient perioperative atrial fibrillation is not exclusionary)
- Planned carotid endarterectomy or carotid artery stenting within 90 days
- Any condition for which there is already an indication for long term anticoagulation Pacemaker or implantable cardioverter defibrillator device
- Work-up for stroke that has already included extended (>48 hour) external ECG (excluding telemetry)
- Stroke and/or comorbid illness will prevent completion of planned follow-up assessments