Pilot Study of Efficacy of Mechanical Insufflation Exsufflation in Stroke

Completed

Phase N/A Results N/A

Trial Description

Stroke patients with dysphagia have restrictive lung dysfunction and impaired cough response. This pilot study was performed to determine if Mechanical Insufflation Exsufflation (MIE) therapy can help recover impaired cough function.

Detailed Description

Mechanical Insufflation- Exsufflation (MI-E) is an assisted coughing machine that has been proven to be very effective in preventing the deterioration of pulmonary function in patients with degenerative neuromuscular disorders. Impaired airway clearance in stroke patients is associated with increased incidence of aspiration pneumonia.
In this pilot study the investigators attempt to assess the efficacy of MI-E as part of a protocol for patients with dysphagia with impaired cough response.

Conditions

Interventions

  • Mechanical Insufflation Exsufflation Device
    Intervention Desc: Mechanical Insufflation Exsufflation -Each patient received daily treatments by means of a light-weight, elastic oronasal mask. Treatments were divided between morning and afternoon and were carried out 5 times a week. A total of 20 sessions were carried out by a a trained respiratory therapist.
    ARM 1: Kind: Experimental
    Label: Mechanical insufflation exsufflation

Trial Design

  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Coughing force as assessed by peak cough flow meter baseline, 2 weeks No
Secondary Maximal inspiratory and expiratory pressure baseline- 2 weeks No
Secondary Cough force during reflexive cough test baseline, 2 weeks No

Sponsors