Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.
20 patients with cervicocephalic arterial dissection will be randomized to open-label aspirin or warfarin, rate of stroke and adverse events will be endpoints.
- Warfarin (Coumadin®)Drug
Other Names: Coumadin; Acenocoumarol ARM 1: Kind: Experimental Label: warfarin
- Aspirin Drug
Other Names: clopidogrel; combination aspirin-dipyridamole ARM 1: Kind: Experimental Label: aspirin
- Allocation: Randomized
- Masking: Open Label
- Purpose: Treatment
- Endpoint: Safety/Efficacy Study
- Intervention: Parallel Assignment
|Type||Measure||Time Frame||Safety Issue|
|Primary||Incidence of stroke by one year.|
|Secondary||Recurrent dissection by one year.|
|Secondary||Incidence of TIA by one year.|
|Secondary||Incidence of major and minor bleeding episodes by one year.|