Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

Withdrawn

Phase 1 Results N/A

Trial Description

Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.

Detailed Description

20 patients with cervicocephalic arterial dissection will be randomized to open-label aspirin or warfarin, rate of stroke and adverse events will be endpoints.

Conditions

Interventions

  • Warfarin (Coumadin┬«)Drug
    Other Names: Coumadin; Acenocoumarol
    ARM 1: Kind: Experimental
    Label: warfarin
  • Aspirin Drug
    Other Names: clopidogrel; combination aspirin-dipyridamole
    ARM 1: Kind: Experimental
    Label: aspirin

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Incidence of stroke by one year.
Secondary Recurrent dissection by one year.
Secondary Incidence of TIA by one year.
Secondary Incidence of major and minor bleeding episodes by one year.

Sponsors