Pilot randomized trial of tissue plasminogen activator in acute ischemic stroke

Completed

Phase N/A Results

Results

Six of ten patients treated with recombinant tissue-type plasminogen activator within 90 minutes improved by 4 or more points at 24 hours compared with one of ten patients in the placebo group (P < .05, Fisher's Exact Test). Two of four patients treated with recombinant tissue-type plasminogen activator within 91-180 minutes improved by 4 or more points at 24 hours compared with two of three patients in the placebo group.