PET-MRI Imaging in Patients With Symptomatic Carotid Artery Stenosis

Not yet recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

• Patients with carotid artery stenosis (>50% for men and >70% for women, by NASCET criteria) above 40 years of age.

Exclusion Criteria

- Patients with new stroke and a modified Rankin score >3
- Chronic kidney disease with an estimated Glomerular Filtration Rate (eGFR) of <30 ml/min/1.73 m2
- Atrial fibrillation
- Pregnant women
- Prior ipsilateral carotid intervention
- Prior neck radiotherapy
- Inability to tolerate the supine position
- Participation in the study would result in delay to surgery
- Psychiatric illness/social situations that would limit compliance with study requirements
- History of allergic reaction attributed to 18F-fluoride
- History of allergic reaction to gadolinium contrast media
- Metal implants and devices including pacemakers and defibrillators