Perfusion Pressure Cerebral Infarction Trial (PPCI) "PPCI"


Phase N/A Results N/A

Summary of Purpose

STUDY HYPOTHESIS In cardiac surgery the volume of perioperative cerebral infarctions can be reduced by increasing mean arterial pressure (MAP) during the cardiopulmonary bypass procedure. BRIEF STUDY SUMMARY Heart surgery using cardiopulmonary bypass (CPB) can be complicated by injury to the brain. Previous studies using brain scans have reported small stroke-like lesions in up to 51% of patients...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 8 April 2016.

1 Jul 2014 7 Jul 2014 1 Jan 2016 1 Apr 2016 1 Apr 2016 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Outcomes Assessor)
  • Purpose: Prevention
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment


  • Anne G. Vedel, MD