Summary of Purpose
To determine the feasibility and safety of using a newly developed perfusion-CT-software to select patients with a favorable penumbra/core-ratio for intravenous thrombolysis in the 3 to 6 hour window after onset of acute ischemic stroke.Read More →
The following dates are available for this trial. Trial information last updated on 2 April 2009.
|Start Date||First Received||1st Completion||Completion||Verification||Results|
To be included, the patients need to have a minimal penumbra size for a given core (infarct) size on the perfusion-CT, according to a progressive linear cut-off table. The cut-off values were selected for maximal potential benefit: the smaller the core size is (and thus the smaller the theoretical bleeding risk), the smaller the penumbra must be to for inclusion. The maximal upper size for inclusion is a core of 30% of the MCA territory (where penumbra must be at least 60%). The trial will be stopped after 4 symptomatic hemorrhages or after 12 patients are enrolled.