To compare a combination therapy of acetylsalicylic acid and dipyridamole with pentoxifylline alone in the prevention of recurrent cerebral ischemic attacks.
- Dipyridamole (Persantine®)Drug
Intervention Desc: Platelet aggregation inhibitor
- Pentoxifylline (Trental®)Drug
Intervention Desc: Vasodilator. In addition, may reduce viscosity or improve erythrocyte flexibility.
Randomized trial of 138 patients at three Buenos Aires hospitals.
Patients were randomized to receive a combination of acetylsalicylic acid and dipyridamole (ASAD, 1,050 mg + 150 mg/day) or pentoxifylline (PTX 1,200 mg/day). Treatment was continued and patients were followed up monthly for 1 year.
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