To study the preventive capacity of a combination of acetylsalicylic acid and dipyridamole and of pentoxifylline in the reduction of morbidity rates in patients with recent TIAs.
- Dipyridamole (Persantine®)Drug
Intervention Desc: Platelet aggregation inhibitor
- Pentoxifylline (Trental®)Drug
Intervention Desc: Vasodilator. In addition, may reduce viscosity or improve erythrocyte flexibility.
Randomized trial of 66 patients at 4 centers.
Patients were randomized to receive either acetylsalicylic acid and dipyridamole (1,050 mg + 150 mg/day) or pentoxifylline (1,200 mg/day). Treatment was continued and patients were followed up monthly for one year.
|Type||Measure||Time Frame||Safety Issue|
|Primary||Recurrent ischemic event.|