Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever "SNIF"


Phase N/A Results N/A

Summary of Purpose

When fever is present in patients with stroke, traumatic brain injury (TBI), or brain hemorrhage, it has been associated with worse outcomes including larger areas of tissue death, increased length of stay, worse degree of coma, lower ability to function, and higher mortality. Both adult and pediatric TBI national... Trial Stopped: Practice change created contamination of usual care arm

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 3 May 2017.

1 Jul 2009 28 Apr 2009 1 Jul 2010 1 Jul 2010 1 May 2017 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment


Not available