To compare the effectiveness of intravenous heparin versus oral aspirin for the treatment of acute ischemic stroke.
- Aspirin (acute stroke) Drug
Intervention Desc: Antiplatelet agent; inhibits thromboxane A2
- Heparin (acute stroke) Drug
Intervention Desc: Intravenous anticoagulant.
Prospective, multi-center, single-blinded, randomized controlled trial.
Patients were randomized to receive either intravenous heparin for 6 days followed by aspirin therapy or oral aspirin 300 mg daily.
|Type||Measure||Time Frame||Safety Issue|
|Primary||Worsening of NIH stroke scale score (NIHSS) by more than 1 point within a week.|
|Secondary||Barthel Index (BI) and Modified Rankin Scale (MRS) at 3 months|