Oral Aspirin vs. Intravenous Heparin for Acute Ischemic Stroke Progression

Completed

Phase N/A Results

Trial Description

To compare the effectiveness of intravenous heparin versus oral aspirin for the treatment of acute ischemic stroke.

Interventions

Trial Design

Prospective, multi-center, single-blinded, randomized controlled trial.

Patient Involvement

Patients were randomized to receive either intravenous heparin for 6 days followed by aspirin therapy or oral aspirin 300 mg daily.

Outcomes

Type Measure Time Frame Safety Issue
Primary Worsening of NIH stroke scale score (NIHSS) by more than 1 point within a week.
Secondary Barthel Index (BI) and Modified Rankin Scale (MRS) at 3 months