Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke "SELECT"

Recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

Eligible patients will be:
1. Adults (≥18years) with the final diagnosis of an acute ischemic stroke
2. CT-Angiogram proven, large artery occlusion (LAO) in the internal carotid artery (ICA), middle cerebral artery (MCA -M1 or M2 site) locations
3. NIH Stroke Scale ≥6 (NIHSS) OR proven LAO on imaging (must be from designated LAO listed on inclusion #2)
4. LSN (last seen normal) to groin puncture (≤ 8 hours) in thrombectomy arm; LSN to presentation to endovascular capable center (≤ 8 hours) in medical arm
5. Baseline modified Rankin Scale score of 0-3
6. Signed Informed Consent obtained
7. Subject willing to comply with the protocol follow-up requirements
8. Anticipated life expectancy of at least 3 months
9. IV-tPA eligible patients must meet AHA guidelines

Exclusion Criteria

Patients are excluded if:
1. Inability to undergo CT-Angiography and/or CT-Perfusion imaging (e.g., renal insufficiency, iodine/contrast allergy)
2. Co-morbid psychiatric or medical illnesses that would confound the neurological assessments