Optimization of Blood Pressure Management After Acute Ischemic Stroke and Its Prognostic Significance


Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- Ischemic stroke survivors within 7 days after onset
- ≥19 year-old male or female
- Medically and neurologically stabilized enough to take BP-lowering medication
- Mean systolic blood pressure ≥135 mm Hg during two days between at least 24 hours after onset and randomization (whether BP-lowering medication was prescribed or not)
- Capable of taking oral medication
- Capable of operating a wireless Bluetooth-equipped sphygmomanometer system and being expected to follow required procedures of the clinical trial
- Patients who provided written informed consent

Exclusion Criteria

- Pregnant, puerperium ≤30 days or on breastfeeding
- enrolled in other interventional clinical trial
- Being transferred to rehabilitation center or institutionalized
- Being expected to have cerebral artery interventions within 3 months after randomization
- Known allergic reactions to olmesartan, amlodipine or hydrochlorothiazide
- Known severe hepatic disease
- Advanced kidney dysfunction requiring dialysis
- Being unlikely, in the opinion of the investigator, to comply with the clinical trial protocol or being unsuitable for any other reason.