Noninvasive Brain Stimulation for Stroke "NIBSstroke"

Recruiting

Phase N/A Results N/A

Trial Description

Noninvasive brain stimulations will be used in acute and chronic stroke patients to improve a variety of functions.

Detailed Description

Noninvasive brain stimulations (NIBS) will be used in acute and chronic stroke patients to improve a variety of functions such as motor functions, cognitive functions, ...
NIBS will be applied in a placebo-controlled, double-blind, randomised fashion. Behavioural data will be collected before and after NIBS, as well as brain functional imaging data.

Conditions

Interventions

  • Tdcs (ELDITH, Neuroconn, Ilmenau, Germany) Device
    Intervention Desc: transcranial direct current stimulation
    ARM 1: Kind: Experimental
    Label: real
    Description: real NIBS
    ARM 2: Kind: Experimental
    Label: sham
    Description: sham NIBS
    ARM 3: Kind: Experimental
    Label: Real stimulation
    Description: real NIBS
    ARM 4: Kind: Experimental
    Label: Sham stimulation
    Description: sham NIBS

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Crossover Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary change in function before/after tDCS Before intervention, immediately after intervention, 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks, 2-3-4-5-6-7-8-9-10-11-12 months No
Secondary change in neuroimaging and neurophysiological before/after tDCS Before intervention, immediately after intervention, 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks, 2-3-4-5-6-7-8-9-10-11-12 months No

Sponsors