Non-invasive Measurement of Cerebral Dynamic Autoregulation "TOMCAT"


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Age greater than or equal to 50 years
- Positive history of at least one of the following vascular disk factors: hypertension, diabetes, hyperlipidemia, coronary artery disease, atrial fibrillation, prior myocardial infarct, transient ischemic attack, or history of smoking

Exclusion Criteria

- Vascular risk factor subjects:
1. Pregnant women
2. Prisoners
3. Prior neurosurgical procedure or traumatic brain injury, including hemicraniectomy or other skull defect
4. Prior history of ischemic or hemorrhagic stroke
5. Prior lower extremity amputation
6. Peripheral vascular disease