NOACs for Stroke Prevention in Patients With Atrial Fibrillation and Previous ICH "NASPAF-ICH"


Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- Previous primary intracerebral hemorrhage
- Atrial fibrillation (CHADS2 ≥ 2)

Exclusion Criteria

- Non-stroke indication for antiplatelet or anticoagulant therapy
- Recent intracerebral hemorrhage within 14 days
- Platelet count less than 100,000/mm3 at enrollment or other bleeding diathesis
- Prior symptomatic lobar intracerebral hemorrhage other than the qualifying event
- Uncontrollable hypertension consistently above SBP/DBP of 160/100 mmHg
- Known hypersensitivity to either ASA or NOACs
- Inability to adhere to study procedures