To investigate the effects of nimodipine in patients with acute ischemic stroke.
- Nimodipine (Nimotop®)Drug
Intervention Desc: Calcium channel blocker (L-type calcium channels)
Randomized, double-blind, parallel-designed trial of 41 patients.
19 patients were treated with nimodipine (40 mg tid. administered for 28 days) and the remaining 22 with placebo, given in identical tablets.
|Type||Measure||Time Frame||Safety Issue|
|Primary||Course and intensity of the neurological deficit were evaluated by the Mathew Scale (slightly modified) as measured at baseline and on days 1, 2, 3, 5, 7, 14, 21, and 28 of treatment..|