Nimodipine in Acute Ischemic Stroke

Completed

Phase N/A Results

Trial Description

To investigate the effects of nimodipine in patients with acute ischemic stroke.

Interventions

  • Nimodipine (NimotopĀ®)Drug
    Intervention Desc: Calcium channel blocker (L-type calcium channels)

Trial Design

Randomized, double-blind, parallel-designed trial of 41 patients.

Patient Involvement

19 patients were treated with nimodipine (40 mg tid. administered for 28 days) and the remaining 22 with placebo, given in identical tablets.

Outcomes

Type Measure Time Frame Safety Issue
Primary Course and intensity of the neurological deficit were evaluated by the Mathew Scale (slightly modified) as measured at baseline and on days 1, 2, 3, 5, 7, 14, 21, and 28 of treatment..