Neuroprotection With Minocycline Therapy for Acute Stroke Recovery Trial "NeuMAST"


Phase 4 Results N/A

Summary of Purpose

Background: Stroke is a leading cause of death and chronic serious disability worldwide. Minocycline, a semisynthetic tetracycline, has consistently been shown in recent years to be neuroprotective in animal models of brain ischemia. Furthermore, a small, open label study done in humans with acute ischemic stroke... Trial Stopped: interim analysis shows futility

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 30 May 2013.

1 Jul 2009 29 Jun 2009 1 Jul 2012 1 Nov 2012 1 May 2013 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


  • Rajinder Singh, Doctor