Neuroprosthesis for Retraining Reaching and Grasping Functions in Severe Hemiplegic Patients

Completed

Phase N/A Results

Trial Description

To compare two types of therapies for upper extremity hemiparesis: conventional physiotherapy and occupationaltherapy to a neuroprosthesis that applies functional electrical stimulation (FES) therapy.

Interventions

Trial Design

Randomized, controlled trial.

Patient Involvement

Patients were randomly assigned to two groups: Group A: the control group who were administered only standard physiotherapy and occupational therapy; and Group B: the treatment group who were trained with the neuroprosthesis in addition to standard physiotherapy and occupational therapy. The Compex Motion electric stimulator (a fully programmable FES system with standard self-adhesive surface stimulation electrodes) was used as a hardware platform for the neuroprosthesis for reaching and grasping. The neuroprosthesis treatment consisted of a functional training program carried out by asking the patient to execute a task with the impaired arm unassisted. The components/sequences of the task the patient was unable to carry out him/her self were assisted with the neuroprosthesis. Patients received treatments of 45 minutes daily, 3 to 5 times per week, for 12 to 16 weeks.

Outcomes

Type Measure Time Frame Safety Issue
Primary Chedoke McMaster Stages of Motor Recovery (CMSMR) test, pertaining to arm and hand functions of the hemiparetic arm. Parts of the Fugl-Meyer Assessment (FMA) pertaining to shoulder, elbow, forearm, wrist, and hand functions of the hemiparetic arm. Functional Independence Measure (FIM) and the Barthel Index (BI).
Secondary Rehabilitation Engineering Laboratory Hand Function Test for Functional Electrical Stimulation Assisted Grasping (REL Test).

Sponsors

Toronto Rehabilitation Institute and the Physicians’ Services Incorporated Foundation.