Neuro-Prävention im Rahmen Des Interventionsprojektes INVADE-2 (Follow-up Studie)

Recruiting

Phase N/A Results N/A

Update History

24 Jan '13
The eligibility criteria were updated.
New
Inclusion Criteria: - signed informed consent for NPV-2 - ongoing participation in INVADE-2 - completed participation in Neuroprävention study (NPV-1) Exclusion Criteria: - not completed Neuroprävention study (Drop-out) - disagreement of notification of incidental findings - lack of capacity to consent of study participant - lack of willingness to cooperate of study participant
Old
Inclusion Criteria: - Participation in INVADE-2-study - signed informed consent - no contraindication for MRI-examination Exclusion Criteria: - Contraindication for MRI-examination - claustrophobia - history of clinical apparent stroke or cerebral bleeding - lack of consent in being told incidental findings - lack of capacity to consent in study participation - lack of capacity to cooperate
11 Oct '12
Trial name was updated.
New
Neuro-Prävention im Rahmen Des Interventionsprojektes INVADE-2 (Follow-up Studie)
The Summary of Purpose was updated.
New
"Silent" strokes are more frequent than clinical apparent strokes and can be detected noninvasively by MRI-investigations of the brain. Persons with silent strokes have a considerably increased risk for clinical apparent strokes as well as for the development of dementia. Intention of the study is the detection of silent strokes and microbleedings by standardized cranial MRI in 1000 participants (500 high-risk and 500 low-risk persons for cerebrovascular accidents) after a standardized neurological and neuropsychological examination. Results will be the base of early detection and early preventive strategies of cerebrovascular accidents in high-risk persons. In the course of a systematic follow-up examination without MRI the same 1000 patients (500 high-risk and 500 low-risk persons for cerebrovascular accidents) will be reinvited to the sites. In addition to the standardized neurological and neuropsychological examinations a surrogate parameter of nephropathy, microalbumin, will be examined as this parameter could be helpful in forecasting cerebral microangiopathy. The clinical investigation will be expanded by several tests in order to assess symptoms of cerebral microangiopathy.
Old
"Silent" strokes are more frequent than clinical apparent strokes and can be detected noninvasively by MRI-investigations of the brain. Persons with silent strokes have a considerably increased risk for clinical apparent strokes as well as for the development of dementia. Intention of the study is the detection of silent strokes and microbleedings by standardized cranial MRI in 1000 participants (500 high-risk and 500 low-risk persons for cerebrovascular accidents) after a standardized neurological and neuropsychological examination. Results will be the base of early detection and early preventive strategies of cerebrovascular accidents in high-risk persons. In the course of a systematic follow-up examination without MRI the same 1000 patients: 500 high-risk and 500 low-risk persons for cerebrovascular accidents will be reinvited to the sites. In addition to the standardized neurological and neuropsychological examinations a surrogate parameter of nephropathy, microalbumin, will be examined as this parameter could be helpful in forecasting cerebral microangiopathy. The clinical investigation will be expanded by several tests in order to assess symptoms of cerebral microangiopathy.
24 Aug '12
A location was updated in Ebersberg.
New
The overall status was updated to "Recruiting" at Dr. Hans C. Gnahn.
A location was updated in Ebersberg.
New
The overall status was updated to "Recruiting" at Praxis Dr. Gnahn.
7 Apr '12
The Summary of Purpose was updated.
New
"Silent" strokes are more frequent than clinical apparent strokes and can be detected noninvasively by MRI-investigations of the brain. Persons with silent strokes have a considerably increased risk for clinical apparent strokes as well as for the development of dementia. Intention of the study is the detection of silent strokes and microbleedings by standardized cranial MRI in 1000 participants (500 high-risk and 500 low-risk persons for cerebrovascular accidents) after a standardized neurological and neuropsychological examination. Results will be the base of early detection and early preventive strategies of cerebrovascular accidents in high-risk persons. In the course of a systematic follow-up examination without MRI the same 1000 patients: 500 high-risk and 500 low-risk persons for cerebrovascular accidents will be reinvited to the sites. In addition to the standardized neurological and neuropsychological examinations a surrogate parameter of nephropathy, microalbumin, will be examined as this parameter could be helpful in forecasting cerebral microangiopathy. The clinical investigation will be expanded by several tests in order to assess symptoms of cerebral microangiopathy.
Old
"Silent" strokes are more frequent than clinical apparent strokes and can be detected non-invasive-ly by MRI-investigations of the brain. Persons with silent strokes have a considerably increased risk for clinical apparent strokes as well as for the development of dementia. Intention of the study is the detection of silent strokes and microbleedings by standadised cranial MRI in 1000 participants (500 high-risk and 500 low-risk persons for cerebrovascular accidents) after a standardised neurological and neuropsychological examination. Results will be the base of early detection and early preventive strategies of cerebrovascular acci-dents in high-risk persons.
29 Feb '12
A location was updated in Ebersberg.
New
The overall status was updated to "Recruiting" at Dr. Hans C. Gnahn.
A location was updated in Ebersberg.
New
The overall status was updated to "Recruiting" at Praxis Dr. Gnahn.