Music Therapy to Restore Motor Deficits After Stroke "NEUROMUSIC"


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  • Penhune VB, Steele CJ. Parallel contributions of cerebellar, striatal and M1 mechanisms to motor sequence learning. Behav Brain Res. 2012 Jan 15;226(2):579-91. doi: 10.1016/j.bbr.2011.09.044. Epub 2011 Oct 6. Review. Pubmed ID:22004979
  • Albert SJ, Kesselring J. Neurorehabilitation of stroke. J Neurol. 2012 May;259(5):817-32. doi: 10.1007/s00415-011-6247-y. Epub 2011 Oct 1. Review. Pubmed ID:21964750
  • Alonso J, Prieto L, Antó JM. [The Spanish version of the SF-36 Health Survey (the SF-36 health questionnaire): an instrument for measuring clinical results]. Med Clin (Barc). 1995 May 27;104(20):771-6. Spanish. Pubmed ID:7783470
  • Altenmüller E, Marco-Pallares J, Münte TF, Schneider S. Neural reorganization underlies improvement in stroke-induced motor dysfunction by music-supported therapy. Ann N Y Acad Sci. 2009 Jul;1169:395-405. doi: 10.1111/j.1749-6632.2009.04580.x. Pubmed ID:19673814
  • Amengual JL, Rojo N, Veciana de Las Heras M, Marco-Pallarés J, Grau-Sánchez J, Schneider S, Vaquero L, Juncadella M, Montero J, Mohammadi B, Rubio F, Rueda N, Duarte E, Grau C, Altenmüller E, Münte TF, Rodríguez-Fornells A. Sensorimotor plasticity after music-supported therapy in chronic stroke patients revealed by transcranial magnetic stimulation. PLoS One. 2013 Apr 17;8(4):e61883. doi: 10.1371/journal.pone.0061883. Print 2013. Pubmed ID:23613966
  • Bangert M, Peschel T, Schlaug G, Rotte M, Drescher D, Hinrichs H, Heinze HJ, Altenmüller E. Shared networks for auditory and motor processing in professional pianists: evidence from fMRI conjunction. Neuroimage. 2006 Apr 15;30(3):917-26. Epub 2005 Dec 27. Pubmed ID:16380270
  • Baumann S, Koeneke S, Schmidt CF, Meyer M, Lutz K, Jancke L. A network for audio-motor coordination in skilled pianists and non-musicians. Brain Res. 2007 Aug 3;1161:65-78. Epub 2007 Jun 4. Pubmed ID:17603027
  • Beck AT, Steer RA, Ball R, Ranieri W. Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. J Pers Assess. 1996 Dec;67(3):588-97. Pubmed ID:8991972
  • Bengtsson SL, Nagy Z, Skare S, Forsman L, Forssberg H, Ullén F. Extensive piano practicing has regionally specific effects on white matter development. Nat Neurosci. 2005 Sep;8(9):1148-50. Epub 2005 Aug 7. Pubmed ID:16116456
  • Byrnes ML, Thickbroom GW, Phillips BA, Wilson SA, Mastaglia FL. Physiological studies of the corticomotor projection to the hand after subcortical stroke. Clin Neurophysiol. 1999 Mar;110(3):487-98. Pubmed ID:10363772
  • Caeiro L, Ferro JM, Costa J. Apathy secondary to stroke: a systematic review and meta-analysis. Cerebrovasc Dis. 2013;35(1):23-39. doi: 10.1159/000346076. Epub 2013 Feb 14. Review. Pubmed ID:23428994
  • CARROLL D. A QUANTITATIVE TEST OF UPPER EXTREMITY FUNCTION. J Chronic Dis. 1965 May;18:479-91. Pubmed ID:14293031
  • Carson AJ, MacHale S, Allen K, Lawrie SM, Dennis M, House A, Sharpe M. Depression after stroke and lesion location: a systematic review. Lancet. 2000 Jul 8;356(9224):122-6. Pubmed ID:10963248
  • Cramer SC, Sur M, Dobkin BH, O'Brien C, Sanger TD, Trojanowski JQ, Rumsey JM, Hicks R, Cameron J, Chen D, Chen WG, Cohen LG, deCharms C, Duffy CJ, Eden GF, Fetz EE, Filart R, Freund M, Grant SJ, Haber S, Kalivas PW, Kolb B, Kramer AF, Lynch M, Mayberg HS, McQuillen PS, Nitkin R, Pascual-Leone A, Reuter-Lorenz P, Schiff N, Sharma A, Shekim L, Stryker M, Sullivan EV, Vinogradov S. Harnessing neuroplasticity for clinical applications. Brain. 2011 Jun;134(Pt 6):1591-609. doi: 10.1093/brain/awr039. Epub 2011 Apr 10. Pubmed ID:21482550
  • Dayan E, Cohen LG. Neuroplasticity subserving motor skill learning. Neuron. 2011 Nov 3;72(3):443-54. doi: 10.1016/j.neuron.2011.10.008. Review. Pubmed ID:22078504
  • Donnan GA, Fisher M, Macleod M, Davis SM. Stroke. Lancet. 2008 May 10;371(9624):1612-23. doi: 10.1016/S0140-6736(08)60694-7. Review. Pubmed ID:18468545
  • Draganski B, Gaser C, Busch V, Schuierer G, Bogdahn U, May A. Neuroplasticity: changes in grey matter induced by training. Nature. 2004 Jan 22;427(6972):311-2. Pubmed ID:14737157
  • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 Nov;12(3):189-98. No abstract available. Pubmed ID:1202204
  • Fugl-Meyer AR, Jääskö L, Leyman I, Olsson S, Steglind S. The post-stroke hemiplegic patient. 1. a method for evaluation of physical performance. Scand J Rehabil Med. 1975;7(1):13-31. Pubmed ID:1135616
  • Gaser C, Schlaug G. Brain structures differ between musicians and non-musicians. J Neurosci. 2003 Oct 8;23(27):9240-5. Erratum in: J Neurosci. 2013 Sep 4;33(36):14629. Pubmed ID:14534258
  • Gowland C, Stratford P, Ward M, Moreland J, Torresin W, Van Hullenaar S, Sanford J, Barreca S, Vanspall B, Plews N. Measuring physical impairment and disability with the Chedoke-McMaster Stroke Assessment. Stroke. 1993 Jan;24(1):58-63. Pubmed ID:8418551
  • Herholz SC, Zatorre RJ. Musical training as a framework for brain plasticity: behavior, function, and structure. Neuron. 2012 Nov 8;76(3):486-502. doi: 10.1016/j.neuron.2012.10.011. Review. Pubmed ID:23141061
  • Hyde KL, Lerch J, Norton A, Forgeard M, Winner E, Evans AC, Schlaug G. Musical training shapes structural brain development. J Neurosci. 2009 Mar 11;29(10):3019-25. doi: 10.1523/JNEUROSCI.5118-08.2009. Pubmed ID:19279238
  • Karni A, Meyer G, Jezzard P, Adams MM, Turner R, Ungerleider LG. Functional MRI evidence for adult motor cortex plasticity during motor skill learning. Nature. 1995 Sep 14;377(6545):155-8. Pubmed ID:7675082
  • Kolb B, Whishaw IQ. Brain plasticity and behavior. Annu Rev Psychol. 1998;49:43-64. Review. Pubmed ID:9496621
  • Krakauer JW. Motor learning: its relevance to stroke recovery and neurorehabilitation. Curr Opin Neurol. 2006 Feb;19(1):84-90. Review. Pubmed ID:16415682
  • Langhorne P, Bernhardt J, Kwakkel G. Stroke rehabilitation. Lancet. 2011 May 14;377(9778):1693-702. doi: 10.1016/S0140-6736(11)60325-5. Review. Pubmed ID:21571152
  • Liepert J, Restemeyer C, Kucinski T, Zittel S, Weiller C. Motor strokes: the lesion location determines motor excitability changes. Stroke. 2005 Dec;36(12):2648-53. Epub 2005 Nov 3. Pubmed ID:16269647
  • Lyle RC. A performance test for assessment of upper limb function in physical rehabilitation treatment and research. Int J Rehabil Res. 1981;4(4):483-92. No abstract available. Pubmed ID:7333761
  • Marin RS, Biedrzycki RC, Firinciogullari S. Reliability and validity of the Apathy Evaluation Scale. Psychiatry Res. 1991 Aug;38(2):143-62. Pubmed ID:1754629
  • Mathiowetz V, Volland G, Kashman N, Weber K. Adult norms for the Box and Block Test of manual dexterity. Am J Occup Ther. 1985 Jun;39(6):386-91. Pubmed ID:3160243
  • Nudo RJ, Wise BM, SiFuentes F, Milliken GW. Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science. 1996 Jun 21;272(5269):1791-4. Pubmed ID:8650578
  • Pantev C, Herholz SC. Plasticity of the human auditory cortex related to musical training. Neurosci Biobehav Rev. 2011 Nov;35(10):2140-54. doi: 10.1016/j.neubiorev.2011.06.010. Epub 2011 Jul 6. Review. Pubmed ID:21763342
  • Parker VM, Wade DT, Langton Hewer R. Loss of arm function after stroke: measurement, frequency, and recovery. Int Rehabil Med. 1986;8(2):69-73. Pubmed ID:3804600
  • Rathore SS, Hinn AR, Cooper LS, Tyroler HA, Rosamond WD. Characterization of incident stroke signs and symptoms: findings from the atherosclerosis risk in communities study. Stroke. 2002 Nov;33(11):2718-21. Pubmed ID:12411667
  • Rojo N, Amengual J, Juncadella M, Rubio F, Camara E, Marco-Pallares J, Schneider S, Veciana M, Montero J, Mohammadi B, Altenmüller E, Grau C, Münte TF, Rodriguez-Fornells A. Music-supported therapy induces plasticity in the sensorimotor cortex in chronic stroke: a single-case study using multimodal imaging (fMRI-TMS). Brain Inj. 2011;25(7-8):787-93. doi: 10.3109/02699052.2011.576305. Epub 2011 May 11. Pubmed ID:21561296
  • Rossini PM, Barker AT, Berardelli A, Caramia MD, Caruso G, Cracco RQ, Dimitrijević MR, Hallett M, Katayama Y, Lücking CH, et al. Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol. 1994 Aug;91(2):79-92. Review. Pubmed ID:7519144
  • Schneider S, Schönle PW, Altenmüller E, Münte TF. Using musical instruments to improve motor skill recovery following a stroke. J Neurol. 2007 Oct;254(10):1339-46. Epub 2007 Jan 27. Pubmed ID:17260171
  • Steele CJ, Bailey JA, Zatorre RJ, Penhune VB. Early musical training and white-matter plasticity in the corpus callosum: evidence for a sensitive period. J Neurosci. 2013 Jan 16;33(3):1282-90. doi: 10.1523/JNEUROSCI.3578-12.2013. Pubmed ID:23325263
  • Truelsen T, Ekman M, Boysen G. Cost of stroke in Europe. Eur J Neurol. 2005 Jun;12 Suppl 1:78-84. Pubmed ID:15877785
  • Wade DT, Langton-Hewer R, Wood VA, Skilbeck CE, Ismail HM. The hemiplegic arm after stroke: measurement and recovery. J Neurol Neurosurg Psychiatry. 1983 Jun;46(6):521-4. Pubmed ID:6875585
  • Wassermann EM, McShane LM, Hallett M, Cohen LG. Noninvasive mapping of muscle representations in human motor cortex. Electroencephalogr Clin Neurophysiol. 1992 Feb;85(1):1-8. Pubmed ID:1371738
  • Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. Pubmed ID:3397865
  • Williams LS, Weinberger M, Harris LE, Clark DO, Biller J. Development of a stroke-specific quality of life scale. Stroke. 1999 Jul;30(7):1362-9. Pubmed ID:10390308
  • Willingham DB. A neuropsychological theory of motor skill learning. Psychol Rev. 1998 Jul;105(3):558-84. Review. Pubmed ID:9697430
  • Zatorre RJ, Chen JL, Penhune VB. When the brain plays music: auditory-motor interactions in music perception and production. Nat Rev Neurosci. 2007 Jul;8(7):547-58. Review. Pubmed ID:17585307

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