Muscle Atrophy, Physical Performance and Glucose Tolerance Post Stroke

Active, not recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Men or women 21 years of age or older
- BMI between 20-50 kg/m2
- Presenting within a month after stroke onset with residual hemiparetic deficit
- Patients must have adequate language and neurocognitive function to participate in testing and give adequate informed consent

Exclusion Criteria

- Patients deemed too disabled to participate in physical therapy, or patients with minimal deficits, or patients who fully recovered after their stroke, in which physical therapy is not necessary
- Unstable angina, CHF, severe PAD
- Dementia or untreated major depression
- Severe receptive or global aphasia
- Heavy alcohol use defined by greater than 3 oz. liquor, 12 oz of wine or 32 oz of beer daily
- Muscle biopsy Exclusion Criteria:
- anti-coagulation therapy with heparin, warfarin, or lovenox (anti-platelet therapy is permitted)
- bleeding disorder
- allergy to lidocaine