Multifocal Brain Magnetic Stimulation in Chronic Ischemic Stroke

Enrolling by invitation

Phase N/A Results N/A

Trial Description

Transcranial magnetic stimulation for post-stroke upper-body motor deficits.

Detailed Description

This study uses transcranial magnetic stimulation of brain motor areas to test whether upper-body motor function can be improved. This is a double-blind study where half of patients will receive real stimulation and half will receive sham (placebo) stimulation.

Conditions

Interventions

  • Transcranial Magnetic Stimulation Device
    Intervention Desc: Transcranial magnetic stimulation delivered through scalp
    ARM 1: Kind: Experimental
    Label: Active treatment
    Description: Active treatment with transcranial magnetic stimulation device.
    ARM 2: Kind: Experimental
    Label: Sham treatment
    Description: Sham treatment with transcranial magnetic stimulation device.

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Percent increase in number and mean intensity (mean T value) of activated voxels in the cortical areas surrounding the lesion on functional MRI One business day before treatment begins, one business day after treatment ends No
Secondary Fugl-Meyer motor arm score One business day before treatment begins, one business day after treatment ends No
Secondary ARAT (Action Research Arm Test) One business day before treatment begins, one business day after treatment ends No
Secondary Hand dynamometer One business day before treatment begins, one business day after treatment ends No
Secondary Pinchmeter score One business day before treatment begins, one business day after treatment ends No
Secondary Timed Up and Go Test One business day before treatment begins, one business day after treatment ends No
Secondary Modified Rankin Scale (mRS) One business day before treatment begins, one business day after treatment ends No

Sponsors