Multicenter Acute Stroke Trial-Europe "MAST-E"


Phase 3 Results

Eligibility Criteria

Inclusion Criteria

Moderate-to-severe ischemia in the territory of the middle cerebral artery presenting within 6 hours of onset.

Exclusion Criteria

Mild deficit (MAST score >55), resolution of symptoms before randomization, CT scan showing cerebral hemorrhage or nonvascular disorder, previous hemorrhagic stroke or previous stroke with secondary sequelae, recent surgery or trauma, other illness known to compromise prognoses, known or suspected pregnancy.