MR-based Collateral Imaging to Predict Response to Endovascular Treatment of Stroke (FAST-COLL Study)

Recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Acute ischemic stroke
- Age 20 years and older
- Disabling stroke defined as a baseline NIHSS > 5 at the time of arrival
- Onset (last-seen-well) time to endovascular treatment time < 12 hours
- Confirmed symptomatic intracranial occlusion, based on CT or MR angiography, at one or more of the following locations: Carotid T/L, M1 MCA, or M1-MCA equivalent (2 or more M2-MCAs)
- Signed informed consent or appropriate signed deferral of consent where approved

Exclusion Criteria

- Baseline non-contrast CT reveals a moderate/large core defined as extensive early ischemic changes of ASPECTS 0-5 in the territory of symptomatic intracranial occlusion.
- Clinical history, past imaging or clinical judgment suggests that the intracranial occlusion is chronic
- Unable to undergo MRI (contraindicated or poor cooperation)
- Patient has a severe or fatal comorbid illness that will prevent improvement or follow-up or that will render the procedure unlikely to benefit the patient
- Pregnant females as determined by positive urine hCG test or lactating females