MR-based Collateral Imaging to Predict Response to Endovascular Treatment of Stroke (FAST-COLL Study)


Phase N/A Results N/A

Trial Description

Based on the results of recent randomized controlled trials, current international guidelines recommend the initiation of endovascular treatment within 6 hours of symptom onset for acute ischemic stroke. Endovascular treatment may be beneficial in selected patients beyond 6 hour time window. In particular, treatment response to endovascular therapy may be greatly influenced by pretreatment collateral status. The aim of this study is to evaluate whether MRI-based collateral imaging (the Fast Analysis SysTem for COLLaterals, 'FAST-COLL') is feasible and can predict the response to endovascular treatment in a wide range of patients with acute ischemic stroke .



  • Endovascular Treatment Procedure
    Other Names: ET
    Intervention Desc: Endovascular mechanical thrombectomy or endovascular delivery of thrombolytic agent

Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Non-Probability Sample

Trial Population

Acute ischemic stroke, eligible for endovascular treatment within 12 hours of symptom onset


Type Measure Time Frame Safety Issue
Primary 90-days functional outcome 90-days No
Secondary Early neurologic improvement 24 hours No
Secondary Symptomatic hemorrhagic transformation During initial admission Yes
Secondary Successful recanalization within 24 hours of symptom onset No