Motor Learning in Stroke Patients and Healthy Volunteers

Completed

Phase N/A Results N/A

Eligibility Criteria

INCLUSION CRITERIA FOR HEALTHY VOLUNTEERS
Age: 18 years to 100 years
Normal physical and neurological examinations
EXCLUSION CRITERIA FOR HEALTHY VOLUNTEERS
Contraindications for transcranial magnetic stimulation: pacemaker, implanted medical pump, metal plate in skull, metal objects inside the eye or skull, history of seizures
INCLUSION CRITERIA FOR STROKE PATIENTS
Age: 18 years to 100 years
Single ischemic or hemorrhagic hemispheric stroke at least one year before enrollment in study, confirmed by neuroimaging studies (computerized tomography or magnetic resonance imaging).
Ability to perform the Jebsen-Taylor test.
EXCLUSION CRITERIA FOR STROKE PATIENTS
More than one stroke.
Other brain lesions (i.e., traumatic brain injury, brain tumor) or neurological problems (i.e., multiple sclerosis, dementia, Parkinson's disease)
Depression or poor motivational capacity
Serious cognitive deficits (defined as equivalent to a mini-mental state exam score of 20 or less).
Inability to understand instructions for the Jebsen-Taylor test.
Uncontrolled medical problems including cardiovascular disease, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease, uncontrolled epilepsy
Contraindications for transcranial magnetic stimulation: pacemaker, implanted medical pump, metal plate in skull, metal objects inside the eye or skull, history of seizures