Motor Excitability Study of High Definition Transcranial Direct Current Stimulation (HD-tDCS) in Chronic Stroke

Recruiting

Phase N/A Results N/A

Trial Description

High definition tDCS will be conducted to both stroke and healthy subjects on primary motor cortex area to explore the motor excitability changes before and after stimulation.

Conditions

Interventions

  • HD-tDCS Device
    Intervention Desc: Different stimulation protocols will be applied to the primary motor cortex of stroke patients
    ARM 1: Kind: Experimental
    Label: Anode HD-tDCS
    Description: The center anode is fixed on the ipsilesional primary motor cortex and the 4 surrounding cathode electrodes will be placed about 6 cm to the center.
    ARM 2: Kind: Experimental
    Label: Cathode HD-tDCS
    Description: The center cathode is fixed on the contralesional primary motor cortex and the 4 surrounding anode electrodes will be placed about 6 cm to the center.
    ARM 3: Kind: Experimental
    Label: Sham HD-tDCS
    Description: The center anode is fixed on the ipsilesional primary motor cortex and the 4 surrounding cathode electrodes will be placed about 6 cm to the center.

Outcomes

Type Measure Time Frame Safety Issue
Primary Electroencephalography (EEG) and Electromyography (EMG) During intervention
Primary Action Research Arm Test (ARAT) Before intervention
Secondary Fugl-Meyer Assessment Upper Extremity (FMA-UE) Before intervention
Secondary Magnetic Resonance Imaging (MRI) Before intervention
Secondary Transcranial Magnetic Stimulation (TMS) Before intervention

Sponsors