Modulation of Cerebral Blood Flow Using Iron Chelators "DFO"

Completed

Phase 0 Results N/A

Eligibility Criteria

Inclusion Criteria

- healthy adults between the ages of 18-80 years.

Exclusion Criteria

- subjects taking vasoactive medications,
- hypertension,
- pregnant women, smokers,
- COPD,
- asthma,
- diabetes mellitus,
- intracranial or carotid stenosis,
- hepatic disease,
- renal disease,
- bone marrow suppression,
- cardiac disease,
- heart failure,
- iron deficiency,
- history of cancer,
- history of head trauma,
- subarachnoid hemorrhage,
- central nervous system vasculitis,
- multiple sclerosis,
- migraines,
- seizures,
- sickle cell disease or trait,
- cardiac arrhythmia,
- unable to give informed consent, or
- poor transcranial Doppler insonation windows.