Mobile Terminal Based Management of Stroke Secondary Prevention Adminstration Effect Research

Not yet recruiting

Phase N/A Results N/A

Trial Description

The investigators want to verify whether mobile application based on stroke strengthen prevention management is more effective than traditional management model or open stroke management platform. Whole blood-impedance based platelet aggregation(WBA) method and VerifyNow detected by aspirin or clopidogrel responsiveness will provide individualized anti-platelet drug selection. Endpoint event is defined as stroke death or relapse. Primary measure outcomes are change of the stroke recurrence rate and mortality after secondary prevention.

Detailed Description

With high incidence, mortality, morbidity and recurrence rateļ¼Œstroke has significant impact on national development strategies planning. Improving secondary prevention will strongly promote stroke management in the rapid developing phase of Chinese economy and expansion of health situation. At present lack of high-quality medical resources, low medical permeability cannot remedy extensive prevention failure of stroke. Mobile healthcare is easier to conduct and still in the early stage of explosive growth. This research group has established an open management platform of stroke prevention. And collaborate with Peking University Institute of Information Technology to develop a smart phone application which can be personalized medication reminder, record medication compliance, home blood pressure and blood glucose test results, also can provide doctor-patient communication platform and symptoms alarm. The investigators want to verify whether mobile application based on stroke strengthen prevention management is more effective than traditional management model or open stroke management platform. Whole blood-impedance based platelet aggregation(WBA) method and VerifyNow detected by aspirin or clopidogrel responsiveness will provide individualized anti-platelet drug selection. Control group will be selected from the National Stroke data registration database platform and open platform for stroke prevention. Follow-up period is 2 years. Endpoint event is defined as stroke death or relapse. Primary measure outcomes are change of the stroke recurrence rate and mortality after secondary prevention.

Conditions

Interventions

  • Mobile terminal Procedure
    Other Names: Mobile Application
    Intervention Desc: multiple strategy including mobile terminal based compliance managment, platelet reactivity modified drug adjustment
    ARM 1: Kind: Experimental
    Label: Mobile terminal
    Description: Stroke received mobile terminal management for secondary prevention administration, as the same time platelet reactivity modified drug selection was performed. Mobile application management conducts the control and regulation for anti hypertension, statin and antiplatelet therapy to increasing drug compliance.
  • Traditional management Procedure
    Other Names: traditional second prevention
    Intervention Desc: aspirin or clopidogrel monotherapy or double treatment for
    ARM 1: Kind: Experimental
    Label: traditional management
    Description: Stroke received traditional management for secondary prevention administration
  • Website platform management Procedure
    Intervention Desc: second prevention based on website platform management
    ARM 1: Kind: Experimental
    Label: website platform management
    Description: Stroke received website platform management for secondary prevention administration. Website platform management conducts the control and regulation for anti hypertension, statin and antiplatelet therapy to increasing drug compliance.

Trial Design

  • Allocation: Non-Randomized
  • Masking: Open Label
  • Purpose: Prevention
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary change of the stroke recurrence rate 2 years stroke recurrence rate No
Secondary change of the stroke mortality 2 years stroke mortality No

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