Mayo Acute Stroke Trial for Enhancing Recovery "MASTER"


Phase 2 Results

Summary of Purpose

This study involves treating patients that have suffered an acute ischemic stroke with the medication donepezil (Aricept ®). The hypothesis is that taking donepezil (FDA-approved for the treatment of Alzheimer's Disease) for the first 90 days following a stroke enhances recovery.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 4 October 2012.

1 Nov 2008 9 Dec 2008 1 Sep 2010 1 Sep 2010 1 Oct 2012 17 Jul 2012
Start Date First Received 1st Completion Completion Verification Results

Trial Basics




Trial Design

  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment


  • 1st Contact: Alexa Richie, MPH, CCRP Phone: 904-953-7839 Email: 2nd Contact: Dale Gamble, CCRP Phone: 904-953-9612 Email: