Manual Dexterity Control After Cerebellar Stimulation "MADECCS"

Not yet recruiting

Phase N/A Results N/A

Trial Description

This study will assess the putative advantages of cerebellar stimulation on motor learning abilities of stroke patients. In order to have a control group to refer to, the effect of cerebellar stimulation on healthy young and old participants will also be assessed.

Detailed Description

Cerebrovascular accidents (CVA) are the first cause of acquired disability in France. Despite rehabilitation interventions, a great proportion of patients suffers from motor disability in the upper limb. Recently, several studies have shown that post CVA patients exhibit great neural plasticity as a direct consequence of their condition.
Interestingly, the transcranial direct current stimulation (tDCS) is a non-invasive electro stimulation technique that allows for a modulation of cerebral activity. It has been shown that when applied to the cerebellum, tDCS increases learning performances of healthy subjects. Yet, motor rehabilitation after a CVA highly relies on motor (re)learning. The cerebellar tDCS thus appear as a promising method to enhance the performance of post-CVA motor learning and consequently the benefits of post-CVA rehabilitation.
The current study aims to promote the post CVA neural plasticity by using the tDCS in order to enhance motor learning of the upper limb.

Conditions

Interventions

  • With stimulation Device
    Intervention Desc: ramp stimulation from 0 to 2 mA followed by 20 minutes of stimulation at 2mA while practicing during 3 of the 4 sessions
    ARM 1: Kind: Experimental
    Label: tDCS Post-CVA
    Description: The participants will get a 20min stimulation at a maximal intensity of 2mA
    ARM 2: Kind: Experimental
    Label: tDCS Young Healthy
    Description: The participants will get a 20min stimulation at a maximal intensity of 2mA
    ARM 3: Kind: Experimental
    Label: tDCS Older Healthy
    Description: The participants will get a 20min stimulation at a maximal intensity of 2mA
  • No stimulation Device
    Intervention Desc: ramp stimulation from 0 to 2 mA followed by 30 sec of stimulation at 2mA.
    ARM 1: Kind: Experimental
    Label: Sham Post-CVA
    Description: The tDCS will be placed as for the Experimental group and will last 30 seconds at the beginning of task
    ARM 2: Kind: Experimental
    Label: Sham Young Healthy
    Description: The tDCS will be placed as for the Experimental group and will last 30 seconds at the beginning of task
    ARM 3: Kind: Experimental
    Label: Sham Older Healthy
    Description: The tDCS will be placed as for the Experimental group and will last 30 seconds at the beginning of task

Outcomes

Type Measure Time Frame Safety Issue
Primary Force control Day 1
Primary Overflow Day 1
Secondary Moberg Pick-up Test Day 1
Secondary Action Research Arm Test Day 1
Secondary Finger time release Day 1

Sponsors