Management of ATherothrombosis with Clopidogrel in High-risk patients with recent TIA or ischemic stroke "MATCH"


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

Patients who experienced ischemic stroke or TIA within 3 months of trial entry and also have at least one additional risk factor (prior ischemic stroke, myocardial infarction (MI), angina pectoris, diabetes mellitus, symptomatic peripheral arterial disease (PAD)).

Exclusion Criteria

Women of childbearing potential and persons who have severe comorbid conditions, inadequately controlled hypertension, severe renal dysfunction or insufficiency, increased risk of bleeding, a history of thrombocytopenia, neutropenia, low platelet, or low neutrophil count, who have any planned carotid endarterectomy, carotid angioplasty, percutaneous coronary anigoplasty, peripheral angioplasty, or any planned major surgery requiring prolonged study drug interruption, who have current or anticipated requirement for oral anticoagulation, an unwillingness to discontinue current antiplatelet treatments, a history of allergy, intolerance, or contra-indication to the use of acetylsalicylic acid or clopidogrel, who have received investigational treatment within the previous 30 days, previously entered into the study, or who are unable to comprehend and provide written informed consent, will be excluded from the study.