Long-term anticoagulation in stroke patients with atrial fibrillation


Phase N/A Results


The rate of recurrent stroke was higher (9.5% v 4.9% P<0.02) but that of major bleeding lower (0.6% v 2.5% P<0.05) with aspirin. The increased stroke rate on aspirin was predominantly due to cardioembolic recurrence in patients presenting initially with cardioembolic stroke (8.4% v 1.9% P<0.01). The recurrence rate in aspirin treated patients who presented with lacunar stroke and atrial fibrillation was similar to that seen in patients receiving warfarin (8.8% v 8.9%).