Left Atrial Appendage Occlusion and Biomarker Evaluation "LABEL"


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- non valvular atrial fibrillation, that makes anticoagulation to prevent embolic stroke from the LAA
- contraindication for the therapy with oral anticoagulants:
- refusal to take oral anticoagulation
- HasBled-score more than 3
- prior bleedings under oral anticoagulation

Exclusion Criteria

- under 18 years
- severely reduced left atrial function
- mechanical heart valve
- pulmonary embolism
- deep vein thrombosis
- myocardial infarction within the last 3 months
- electrical cardioversion within 30 days after potential occluder implantation
- atrial septum defect or interventional/surgical occlusion of ASD
- status after heart transplant
- symptomatic carotid artery stenosis
- transient ischemic attack (TIA) or stroke within last 30 days
- intracerebral bleeding within the last 2 months
- acute infection
- existing or planned pregnancy